Ultra-LEAF™ Purified anti-mouse CD314 (NKG2D) Antibody, CD314, CX5,BioLegend,130218

To reduce non-specific binding, preincubate cells with purified anti-mouse CD16/CD32, clone 93 (Cat No 101301/2) is recommended.This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes contact The Regents of the University of California.

Host

Rat

Reactivity

Mouse

Application

FC -Quality testedBlock -Reported in the literature, not verified in house

Platform ID

BAB654276585

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameUltra-LEAF™ Purified anti-mouse CD314 (NKG2D) Antibody, CD314, CX5
Cat. No.130218
HostRat
RRIDAB_2832469 (BioLegend Cat. No. 130217)AB_2832470 (BioLegend Cat. No. 130218)
IsotypeRat IgG1, κ
ReactivityMouse
ApplicationFC -Quality testedBlock -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberCX5
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetCD314
ImmunogenMouse NKG2D
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only

Scientific Background

This antibody has been reported to block binding of NKG2D to its ligands, RAE-1 and H60, and inhibition of NKG2D-dependent NK-cell cytotoxicity.

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