Ultra-LEAF™ Purified anti-mouse CD49d Antibody, CD49d, R1-2,BioLegend,103630

The R1-2 antibody has been shown to partially block CD49d mediated interactions and, in combination with the 9C10 (MFR4.B) antibody, completely blocks VCAM-1 binding to VLA-4. Additional reported applications (for the relevant formats) include:in vitroandin vivoblocking of cell-cell adhesion and T cell costimulation1-4, immunoprecipitation1, and immunohistochemistry of frozen sections5. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No.103629 and 103630).

Host

Rat

Reactivity

Mouse

Application

FC -Quality testedIP, Block, IHC-F -Reported in the literature, not verified in house

Platform ID

BAB083338123

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameUltra-LEAF™ Purified anti-mouse CD49d Antibody, CD49d, R1-2
Cat. No.103630
HostRat
RRIDAB_2832313 (BioLegend Cat. No. 103629)AB_2832314 (BioLegend Cat. No. 103630)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC -Quality testedIP, Block, IHC-F -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberR1-2
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetCD49d
ImmunogenAKR/Cum mouse spontaneous T lymphoma line TK1
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only

Scientific Background

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