Ultra-LEAF Purified anti-mouse/human LAP TGF-beta1 Antibody anti-LAP - TW7-28G11,BioLegend,146704
Several anti-LAP antibody clones have been compared and characterized for their LAP reactivity.2TW7-28G11 recognizes conformation specific latent TGF-β complex (LAP + TGF-β) and pro-TGF-β1, but not free LAP or active TGF-β.Additional reported applications (for relevant formats) include: Western blotting1, immunoprecipitation1, and neutralization2. TW7-28G11 is able to neutralize TGF-β activity.
Host
Mouse
Reactivity
Mouse, Human
Application
FC - Quality testedWB, IP, Neut - Reported in the literature, not verified in house
Platform ID
BAB909587770
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameUltra-LEAF Purified anti-mouse/human LAP TGF-beta1 Antibody anti-LAP - TW7-28G11
Cat. No.146704
HostMouse
RRIDAB_2562709 (BioLegend Cat. No. 146703)AB_2562710 (BioLegend Cat. No. 146704)
IsotypeMouse IgG2b, κ
ReactivityMouse, Human
ApplicationFC - Quality testedWB, IP, Neut - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberTW7-28G11
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetLAP
ImmunogenMouse Tgfb1'transduced P3U1 cells
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
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