Ultra-LEAF™ anti-human CD275 (B7-H2, ICOSL) Antibody, CD275, W21036I,BioLegend,387506
Clone W21036I completely blocks clone 9F.8A4 but does not block clone 2D3.
Host
Rat
Reactivity
Human
Application
Block - Quality tested
Platform ID
BAB148506827
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameUltra-LEAF™ anti-human CD275 (B7-H2, ICOSL) Antibody, CD275, W21036I
Cat. No.387506
HostRat
RRIDAB_3083390 (BioLegend Cat. No. 387505)AB_3083390 (BioLegend Cat. No. 387506)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationBlock - Quality tested
ClonalityMonoclonal
Clone NumberW21036I
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetCD275
ImmunogenHuman B7-H2 recombinant protein (19-258 aa)
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
B7-H2, a member of the B7 family and the immunoglobulin superfamily, is a 40 kD protein also known as B7RP-1, B7h, B7-H2, GL50 and ICOS Ligand. Human B7-H2 is expressed by B lymphocytes, activated monocytes/macrophages, and dendritic cells. B7-H2 binds to a CD28-like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. The interaction of ICOS with B7-H2 plays an important role in the T cell costimulation pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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