VASP Antibody (YA6215),MedChemexpress,HY-P86523

VASP Antibody (YA6215) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VASP.

Host

Rabbit

Reactivity

Human

Application

WB,IHC-P,ICC/IF,IP,ELISA

Conjugate

Non-conjugated

Platform ID

BAB663787421

Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Scientific Background
Synonyms

Specifications

NameVASP Antibody (YA6215)
Cat. No.HY-P86523
Accession NumberP50552
Gene ID (Entrez)7408
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,IP,ELISA
Working DilutionsIHC-P: 1:200-1:1000; WB: 1:1000-1:5000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200
ClonalityMonoclonal
Clone NumberYA6215
Molecular WeightPredicted band size: 40 kDa; Observed band size: 50 kDa
PurityProtein A
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

VASP (Ena/VASP proteins) are actin-associated proteins involved in processes dependent on cytoskeleton remodeling and cell polarity, including axon guidance, lamellipodial and filopodial dynamics, platelet activation, and cell migration. VASP promotes actin filament elongation by protecting the barbed end of growing filaments from capping and enhancing actin polymerization rates in the presence of capping protein. It stimulates elongation by transferring profilin-bound actin monomers to the barbed end. VASP also plays a role in Listeria monocytogenes' actin-based motility within host cells and regulates actin dynamics in platelets, contributing to platelet aggregation control.

Synonyms

VASP; Vasodilator-stimulated phosphoprotein; VASP

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