VEGF Receptor 1 (phospho Tyr1213) antibody,Genetex,GTX55404
Host
Rabbit
Reactivity
Human
Application
WB
Conjugate
Unconjugated
Platform ID
BAB259021341
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Specifications
Scientific Background
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
Synonyms
fms related tyrosine kinase 1 , FLT , FLT-1 , VEGFR-1 , VEGFR1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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