VEGFA antibody [4G3],Genetex,GTX83425

Host

Mouse

Reactivity

Human, Dog

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB630699172

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameVEGFA antibody [4G3]
Cat. No.GTX83425
Gene ID (Entrez)7422
HostMouse
IsotypeIgG2b
ReactivityHuman, Dog
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityMonoclonal
Concentration0.46 mg/ml (Please refer to the vial label for the specific concentration.)
TargetVEGFA
ImmunogenHuman recombinant protein fragment corresponding to amino acids 27-233 of human VEGFA (NP_003367) produced in E.coli.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Synonyms

vascular endothelial growth factor A , MVCD1 , VEGF , VPF

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