WHSC2 Antibody (YA4494)(PBS only),MedChemexpress,HY-P84797A

WHSC2 Antibody (YA4494) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to WHSC2.

Host

Mouse

Reactivity

Human,Rat

Application

WB,IHC-P,ICC/IF,FC,ELISA

Conjugate

Non-conjugated

Platform ID

BAB640587298

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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MedChemexpress

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameWHSC2 Antibody (YA4494)(PBS only)
Cat. No.HY-P84797A
Accession NumberQ9H3P2 
Gene ID (Entrez)7469
HostMouse
IsotypeIgG2b
ReactivityHuman,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,FC,ELISA
Working DilutionsWB: 1:500-1:2000; IHC-P: 1:200-1:1000; ICC/IF: 1:200-1:1000; FC: 1:200-1:400; ELISA: 1:10000
Clone NumberYA4494
Molecular WeightPredicted band size: 57.3 kDa; Observed band size: 49 kDa
ImmunogenPurified recombinant fragment of human WHSC2 (AA: 280-511) expressed in E. Coli.
Purityaffinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, pH 7.4.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

WHSC2 is an essential component of the NELF complex, which negatively regulates RNA polymerase II transcriptional elongation by associating with the DSIF complex to induce transcriptional pausing. This effect is counteracted by the P-TEFb kinase complex. (Microbial infection context) The NELF complex participates in HIV-1 latency, potentially through recruiting PCF11 to paused RNA polymerase II. by similar: Functional descriptions align with other NELF complex components.

Synonyms

NELFA; NELF-A; P/OKcl.15

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