XRCC1 Antibody (YA1058),MedChemexpress,HY-P81314

XRCC1 Antibody (YA1058) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to XRCC1.

Host

Mouse

Reactivity

Human

Application

WB

Conjugate

Non-conjugated

Platform ID

BAB756765299

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Scientific Background
Synonyms

Specifications

NameXRCC1 Antibody (YA1058)
Cat. No.HY-P81314
Accession NumberP18887
Gene ID (Entrez)7515
HostMouse
IsotypeIgG1
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB
Working DilutionsWB: 1:500-1:1000
ClonalityMonoclonal
Clone NumberYA1058
Molecular WeightPredicted band size: 69 kDa; Observed band size: 82 kDa
ImmunogenPurified recombinant human XRCC1 protein fragments expressed in E.coli.
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by The related gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. The protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiorelated genesis and recombination in germ cells. A rare microsatellite polymorphism in The related gene is associated with cancer in patients of varying radiosensitivity.

Synonyms

XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1

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