XRCC6BP1 antibody,Genetex,GTX66132

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB292605213

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameXRCC6BP1 antibody
Cat. No.GTX66132
Gene ID (Entrez)91419
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetATP23
ImmunogenRecombinant funsion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1).
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Synonyms

ATP23 metallopeptidase and ATP synthase assembly factor homolog , KUB3 , XRCC6BP1

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