ZCRB1 antibody,Genetex,GTX85274

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ELISA

Conjugate

Unconjugated

Platform ID

BAB449352467

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameZCRB1 antibody
Cat. No.GTX85274
Gene ID (Entrez)85437
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetZCRB1
ImmunogenZCRB1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZCRB1.The immunogen is located within the last 50 amino acids of ZCRB1.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.

Synonyms

zinc finger CCHC-type and RNA binding motif containing 1 , MADP-1 , MADP1 , RBM36 , SNRNP31 , ZCCHC19

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