Zebrafish DRD4 Antibody / Dopamine Receptor D4 Antibody (RZ1414),NSJ Bioreagent,RZ1414

Host

Rabbit

Reactivity

Zebrafish

Platform ID

BAB604639961

Suppliers

(44)

MoreBio Inc.

+82-2-406-2942

Country:South Korea
City:Hanam-si
Morebio Inc., 25 Misa Riverbyeon-seo, Hanam-si, Gyeonggi-do, Testa Tower F810 (12918)

Biomax Scientific Sdn Bhd

+60-33-122-7461

Country:Malaysia
12, Jalan Temenggong Taman Desawira, 42500 Telok P. Garang Selangor, Malaysia

Interlab Co. Ltd

+886-22-736-7100

Country:Taiwan, China
4th floor, No. 149-17, Section 2, Keelung Road, Taipei,China- Taiwan 110

NSJ Bioreagent

Headquarters

9921 Carmel Mountain Rd 352 San Diego CA 92129

Contact

Tel: 858.663.9055
Fax:

Product Specifications
Scientific Background

Specifications

NameZebrafish DRD4 Antibody / Dopamine Receptor D4 Antibody (RZ1414)
Cat. No.RZ1414
Accession NumberA0A0R4IR92
HostRabbit
IsotypeRabbit Ig
ReactivityZebrafish
Working DilutionsWestern Blot : 0.5-1ug/ml
ClonalityPolyclonal (rabbit origin)
Formulation0.5mg/ml if reconstituted with 0.2ml sterile DI water
StorageAfter reconstitution, the Zebrafish DRD4A Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Scientific Background

Zebrafish DRD4 Antibody / Dopamine Receptor D4 Antibody recognizes DRD4A, a member of the dopamine receptor family and the class A rhodopsin-like G protein-coupled receptor (GPCR) superfamily. Dopamine receptors mediate the actions of dopamine, an essential neurotransmitter that regulates behavior, cognition, movement, motivation, learning, and neuroendocrine signaling. Upon activation by dopamine, DRD4 receptors primarily couple to inhibitory G proteins that modulate intracellular signaling pathways and influence neuronal excitability and synaptic communication.Zebrafish DRD4 Antibody is valuable for studying dopaminergic signaling pathways during vertebrate development. Dopamine plays critical roles in nervous system formation, neuronal differentiation, and establishment of neural circuits. Expression of DRD4 receptors contributes to the regulation of neurotransmission and cellular responses that influence behavioral and physiological processes. Because zebrafish provide a powerful model for in vivo neurodevelopmental studies, analysis of DRD4 expression can help elucidate mechanisms that govern nervous system organization and function.Zebrafish DRD4 Antibody is also useful for investigations of brain function, behavior, and neuromodulatory signaling. Dopamine receptors participate in pathways that regulate locomotion, sensory processing, reward-associated behaviors, and cognitive activity. Alterations in dopaminergic signaling can significantly impact neuronal communication and behavioral outcomes. Consequently, DRD4 has become an important target for studies examining neurotransmitter regulation and neural network activity in vertebrate systems.Zebrafish DRD4 Antibody supports research involving GPCR biology, neurotransmitter signaling, neurodevelopment, and behavioral neuroscience. The evolutionary conservation of dopaminergic pathways between zebrafish and mammals makes zebrafish an attractive model for studying the molecular mechanisms that control dopamine-dependent cellular responses. Expression analysis of DRD4 can provide insights into receptor localization, neuronal function, and the regulation of signaling pathways involved in brain development and physiology.Zebrafish DRD4 Antibody is additionally relevant for studies examining neurological disorders and neuropharmacology. Dopamine receptors represent important therapeutic targets and are widely investigated in relation to cognition, attention, motivation, and neuropsychiatric disease mechanisms. As a result, DRD4 remains an important biomarker for investigations of dopaminergic signaling, receptor regulation, and vertebrate nervous system biology.This Zebrafish antibody is part of a broaderZebrafish / Danio rerio antibody paneloffered by NSJ Bioreagents.

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