alpha-Smooth Muscle Actin (1A4) Mouse Monoclonal Antibody (BSA and Azide Free)#69319,Cell Signaling Technology (CST),69319

alpha-Smooth Muscle Actin (1A4) Mouse Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total α-smooth muscle actin protein.

Host

Mouse

Reactivity

Human, Mouse, Rat, Hamster

Platform ID

BAB150383397

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Product Specifications
Scientific Background
Synonyms

Specifications

Namealpha-Smooth Muscle Actin (1A4) Mouse Monoclonal Antibody (BSA and Azide Free)#69319
Cat. No.69319
Accession NumberP62736
Gene ID (Entrez)62736
HostMouse
SensitivityEndogenous
ReactivityHuman, Mouse, Rat, Hamster
Molecular Weight42
ImmunogenIgG2a
FormulationThis product is the carrier free version of product #56856. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol.This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN, or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, pleasecontact us. Optimal dilutions/concentrations should be determined by the end user.BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.
StorageStore at -20°C.This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles.A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
Regulatory StatusResearch Use Only

Scientific Background

Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic β- and γ-actin proteins are referred to as “non-muscle” actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility (1). The α-cardiac and α-skeletal actin proteins are expressed in striated cardiac and skeletal muscles, respectively. The smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is also known as aortic smooth muscle actin. These actin isoforms regulate the contractile potential of muscle cells (1).Herman, I.M. (1993)Curr Opin Cell Biol5, 48-55.Alternate NamesAAT6; ACTA; ACTA2; actin alpha 2, smooth muscle; actin, alpha 2, smooth muscle, aorta; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha 2 actin; alpha smooth muscle Actin; Alpha-actin-2; alpha-cardiac actin; Cell growth-inhibiting gene 46 protein; growth-inhibiting gene 46; smooth muscle actin

Synonyms

AAT6; ACTA; ACTA2; actin alpha 2, smooth muscle; actin, alpha 2, smooth muscle, aorta; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha 2 actin; alpha smooth muscle Actin; Alpha-actin-2; alpha-cardiac actin; Cell growth-inhibiting gene 46 protein; growth-inhibiting gene 46; smooth muscle actin

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.