alpha-Smooth Muscle Actin (1A4) Mouse Monoclonal Antibody (BSA and Azide Free)#69319,Cell Signaling Technology (CST),69319
alpha-Smooth Muscle Actin (1A4) Mouse Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total α-smooth muscle actin protein.
Host
Mouse
Reactivity
Human, Mouse, Rat, Hamster
Platform ID
BAB150383397
Cell Signaling Technology (CST)
Contact
Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355
Email:
Specifications
Scientific Background
Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic β- and γ-actin proteins are referred to as “non-muscle” actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility (1). The α-cardiac and α-skeletal actin proteins are expressed in striated cardiac and skeletal muscles, respectively. The smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is also known as aortic smooth muscle actin. These actin isoforms regulate the contractile potential of muscle cells (1).Herman, I.M. (1993)Curr Opin Cell Biol5, 48-55.Alternate NamesAAT6; ACTA; ACTA2; actin alpha 2, smooth muscle; actin, alpha 2, smooth muscle, aorta; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha 2 actin; alpha smooth muscle Actin; Alpha-actin-2; alpha-cardiac actin; Cell growth-inhibiting gene 46 protein; growth-inhibiting gene 46; smooth muscle actin
Synonyms
AAT6; ACTA; ACTA2; actin alpha 2, smooth muscle; actin, alpha 2, smooth muscle, aorta; Actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha 2 actin; alpha smooth muscle Actin; Alpha-actin-2; alpha-cardiac actin; Cell growth-inhibiting gene 46 protein; growth-inhibiting gene 46; smooth muscle actin
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