alpha Synuclein antibody [4B12],Genetex,GTX21904

Host

Mouse

Reactivity

Human

Application

WB IHC-P IHC-Fr Dot ELISA IHC

Conjugate

Unconjugated

Platform ID

BAB299824275

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Namealpha Synuclein antibody [4B12]
Cat. No.GTX21904
Gene ID (Entrez)6622
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P IHC-Fr Dot ELISA IHC
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSNCA
ImmunogenRecombinant human alpha synuclein produced in E. coli.
PurityAmmonium sulfate precipitated and dialyzed tissue culture supernatant.
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Synonyms

synuclein alpha , NACP , PARK1 , PARK4 , PD1

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