alpha Synuclein (phospho Ser129) antibody,Genetex,GTX02537

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB469088047

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Namealpha Synuclein (phospho Ser129) antibody
Cat. No.GTX02537
Gene ID (Entrez)6622
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSNCA
ImmunogenA synthesized peptide derived from human Synuclein alpha around the phosphorylation site of Ser129.
PurityPurified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columnsFrom serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Synonyms

synuclein alpha , NACP , PARK1 , PARK4 , PD1

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