anti-human ACE-2 monoclonal antibody Anti-Human 100 µg,Reliatech,101-M201

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human ACE-2 recombinant protein (extracellular domain)

Host

Mouse

Reactivity

Human

Application

WB, IHC (P)

Platform ID

BAB057929176

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human ACE-2 monoclonal antibody Anti-Human 100 µg
Cat. No.101-M201
Accession NumberQ9BYF1
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB, IHC (P)
Clone Number(#11A31)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

The protein encoded by the gene ACE belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Synonyms

ACE2; ACEH

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