anti-human CD19 monoclonal antibody Anti-Human 50 µg,Reliatech,101-M194

Host

Mouse

Reactivity

Human

Application

FC

Platform ID

BAB058828744

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human CD19 monoclonal antibody Anti-Human 50 µg
Cat. No.101-M194
Accession NumberP15391
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFC
Clone Number(#13Q82)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

B-lymphocyte antigen CD19 is a surface protein of the immunoglobulin superfamily. It binds to the B cell receptor on the cell surface of B cells and lowers the threshold of its activability. Thus, overexpression of CD19 in mice, as well as knockout mice, shows that CD19 affects the signaling threshold of receptors that regulate B lymphocyte selection, activation, and differentiation. At the molecular level, CD19 is involved in the activation of phosphatidylinositol 4,5-bisphosphate 3-kinases (PI3K). It is glycosylated and phosphorylated. Translated with www.DeepL.com/Translator (free version)

Synonyms

B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12

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