anti-human Cathepsin E monoclonal antibody Anti-Human 100 µg,Reliatech,101-M248

Cathepsin E is an intracellular aspartic protease of the pepsin family. Unlike Cathepsin D, another member of the same family and a lysosomal protease with relatively ubiquitous distribution, Cathepsin E is not a lysosomal enzyme and has a limited cell and tissue distribution. However, both Cathepsin D and E play an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. Both enzymes are efficient in cleaving Swedish mutant of amyloid precursor protein (APP) at the β site but show almost no reactivity with wildtype APP. Human Cathepsin E is synthesized as a precursor protein, consisting of a signal peptide (aa 1-17), a propeptide (aa 18-53), and a mature chain (aa 54-396).

CTSE; CATE