anti-human Complement MASP3 monoclonal antibody Anti-Human 50 µg,Reliatech,101-M336

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Complement MASP3.

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB434316010

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human Complement MASP3 monoclonal antibody Anti-Human 50 µg
Cat. No.101-M336
Accession NumberP48740
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB
Clone Number(#4F19)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Nine serine proteases and their cofactors participate in the three pathways that lead to complement activation. C1r and C1s are the first two proteases that trigger the classical pathway. Three mannan-binding lectin-associated serine proteases (MASPs) are involved in the MBL pathway. C2 is involved in both the classical and the MBL pathways. Factor D is the first protease that activates the alternative pathway, which also includes proteases factor B and factor I. C3 plays a central role in both classical and alternative pathways. C3d, one of its fragments, binds to CR2. C5 is common to all three pathways, and C5a belongs to a family of related proteins known as anaphylatoxins.

Synonyms

MASP1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1

Category Paths

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