anti-human DCIR (CLEC4A) monoclonal antibody Anti-Human 50 µg,Reliatech,101-M375

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant DCIR (also called CLEC4A or CLEC6) extracellular domain.

Host

Mouse

Reactivity

Human

Application

WB, FC

Platform ID

BAB809703324

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human DCIR (CLEC4A) monoclonal antibody Anti-Human 50 µg
Cat. No.101-M375
Accession NumberQ9UMR7
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB, FC
Clone Number(#5P20)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

DCIR, also known as Lectin-like Immunoreceptor (LLIR), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosinebased inhibitory motif (ITIM) in its cytoplasmic domain. Besides DC, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.

Synonyms

CLEC4A; DCIR; LLIR; DDB27; CLECSF6; HDCGC13P

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