anti-human DMP-1 monoclonal antibody Anti-Human 100 µg,Reliatech,101-M579

Host

Mouse

Reactivity

Human

Application

E

Platform ID

BAB434815770

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human DMP-1 monoclonal antibody Anti-Human 100 µg
Cat. No.101-M579
Accession NumberQ13316
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationE
Clone Number(#35K29)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Dentin matrix acidic phosphoprotein 1 is a protein that in humans is encoded by the DMP1 gene. DMP1 is an extracellular matrix protein and a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family (other members being DSPP, IBSP, MEPE, and SPP1). This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional Arg-Gly-Asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes.

Synonyms

Dentin matrix acidic phosphoprotein 1, DMP-1; Dentin matrix protein 1

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