anti-human Dihydrofolate Reductase monoclonal antibody Anti-Human 50 µg,Reliatech,101-M365

Host

Mouse

Reactivity

Human

Application

WB, IHC (P), ICC

Platform ID

BAB559778288

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human Dihydrofolate Reductase monoclonal antibody Anti-Human 50 µg
Cat. No.101-M365
Accession NumberP00374
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB, IHC (P), ICC
Clone Number(#24A8)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Dihydrofolate reductase (DHFR), also called dihydrofolic acid reductase, are enzymes that hydrogenate folic acid to dihydrofolic acid (DHF) and DHF to tetrahydrofolic acid (THF). These reactions activate the vitamin folic acid and are essential for nucleotide biosynthesis in all living organisms. In humans, DHFR is found in all tissue types. Mutations at the DHFR gene can cause dihydrofolate reductase deficiency, and this megaloblastic anemia.

Synonyms

Dihydrofolate reductase

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