anti-human Enteropeptidase monoclonal antibody Anti-Human 100 µg,Reliatech,101-M388

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with human recombinant Enteropeptidase (also called Enterokinase). The IgG fraction of culture supernatant was purified by Protein G affinity chromat

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB934965698

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human Enteropeptidase monoclonal antibody Anti-Human 100 µg
Cat. No.101-M388
Accession NumberP98073
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB
Working DilutionsWestern Blot: Use at 250 ng/ml-1 µg/ml
Clone Number(#8S12)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Enteropeptidase/Enterokinase initiates activation of pancreatic proteases by converting trypsinogen to trypsin, which in turn activates chymotrypsin, carboxypeptidases and elastases. Located in intestinal brush border, it is a disulfide bond linked dimer of the heavy and light chains, which are derived from the same single-chain precursor. The multi-domain-containing the heavy chain consists of a short cytoplasmic tail, a transmembrane, a SEA, a SRCR, a MAM, two CUB and two LDL-receptor class A domains. The light chain contains the catalytic domain of trypsin-like serine proteases.

Synonyms

TMPRSS15; ENTK; PRSS7; Enterokinase; Serine protease 7; Transmembrane protease serine 15

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