anti-human FGFR-3 (IIIC) monoclonal antibody Anti-Human 100 µg,Reliatech,101-M737

The antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with the recombinant extracellular domain of human Fibroblast Growth Factor Receptor-3 (sFGFR-3). The IgG1 fraction of the tissue culture supernatant

Host

Mouse

Reactivity

Human

Application

WB, IHC (F)

Platform ID

BAB310353012

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human FGFR-3 (IIIC) monoclonal antibody Anti-Human 100 µg
Cat. No.101-M737
Accession NumberP22607
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB, IHC (F)
Clone Number(#6G72)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.

Synonyms

FGFR3; ACH; CEK2; JTK4; CD333; HSFGFR3EX

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