anti-human FGFR-3 neutralizing antibody monoclonal antibody Anti-Human 100 µg,Reliatech,500-002

Host

E. coli

Reactivity

human

Platform ID

BAB622859259

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human FGFR-3 neutralizing antibody monoclonal antibody Anti-Human 100 µg
Cat. No.500-002
Accession NumberP22607
HostE. coli
IsotypeFab-Fragment
Reactivityhuman
Clone NumberRecombinant IG
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
StorageLyophilized samples are stable for up to a year at -20°C. Upon reconstitution, the Fab is stable for up to 1 month at 4°C or up to 1 year at -20°C.
Regulatory StatusFor research use only

Scientific Background

Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.

Synonyms

FGFR3; ACH; CEK2; JTK4; CD333; HSFGFR3EX

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