anti-human GDNF R alpha 3 monoclonal antibody Anti-Human 100 µg,Reliatech,101-M439

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of GDNF-Ra3.

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB435615386

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human GDNF R alpha 3 monoclonal antibody Anti-Human 100 µg
Cat. No.101-M439
Accession NumberO60609
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB
Clone Number(#2P25)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

GDNF family receptor alpha-1 is a protein that in humans is encoded by the GFRA1 gene. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms

glial cell line derived neurotrophic factor receptor alpha 3

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