anti-human IL-1 receptor antagonist monoclonal antibody Anti-Human 100 µg,Reliatech,101-M501
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with human recombinant protein of IL-1ra.
Host
Rat
Reactivity
Human
Application
WB
Platform ID
BAB373633887
Reliatech
Contact
Tel: +49 (0) 5331 - 8586987
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Product Specifications
Scientific Background
Synonyms
Specifications
Nameanti-human IL-1 receptor antagonist monoclonal antibody Anti-Human 100 µg
Cat. No.101-M501
Accession NumberP18510
HostRat
IsotypeIgG2
ReactivityHuman
ApplicationWB
Working DilutionsWB: 1:500-2000
Clone Number(#2V23)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only
Scientific Background
IL-1 receptor antagonist (IL-1ra) was originally isolated from the urine of patients with monocytic leukemia and has also been purified from adherent monocytes. The protein shows 26% amino acid homology to IL-1 beta and 19% homology to IL-1 alpha. It will compete with either factor for receptor binding, but does not interact with either one. Human IL-1ra will bind to both types of IL-1 receptor (I and II) on human cells. In mouse, IL-1RII does not bind IL-1ra.
Synonyms
IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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