anti-human Insulin R monoclonal antibody Anti-Human 100 µg,Reliatech,101-M514

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Insulin R (also called CD220) extracellular domain.

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB249271081

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human Insulin R monoclonal antibody Anti-Human 100 µg
Cat. No.101-M514
Accession NumberP06213
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB
Clone Number(#2A12)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

The insulin receptor is a type I transmembrane receptor tyrosine kinase. Ligand binding results in receptor autophosphorylation, and subsequent downstream signaling important in metabolic regulation, cell growth, differentiation, and apoptosis. Mutations in the insulin receptor gene have been linked to insulin-resistant diabetes mellitus and noninsulin-dependent diabetes mellitus.

Synonyms

INSR; HHF5; CD220

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