anti-human Jagged-1 monoclonal antibody Anti-Human 50 µg,Reliatech,101-M524
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Jagged-1.
Host
Mouse
Reactivity
Human
Application
WB, FC
Platform ID
BAB686839798
Reliatech
Contact
Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989
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Product Specifications
Scientific Background
Synonyms
Specifications
Nameanti-human Jagged-1 monoclonal antibody Anti-Human 50 µg
Cat. No.101-M524
Accession NumberP78504
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB, FC
Clone Number(#4A24)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only
Scientific Background
JAG1 is a protein associated with Alagille syndrome. JAG1 has also been designated as CD339 (cluster of differentiation 339). The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Synonyms
JAG1; AGS; AHD; AWS; HJ1; CD339; JAGL1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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