anti-human LOX-1 monoclonal antibody Anti-Human 50 µg,Reliatech,101-M557

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of LOX-1 (also called scavenger receptor class E member 1 (SR-E1)).

Host

Mouse

Reactivity

Human

Application

WB, N

Platform ID

BAB062127160

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human LOX-1 monoclonal antibody Anti-Human 50 µg
Cat. No.101-M557
Accession NumberP78380
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB, N
Clone Number(#1L36)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Lectin-like Oxidized Low-density Lipoprotein Receptor 1 (LOX-1), also known as Oxidized Low-density Lipoprotein Receptor 1 (OLR1), is a type II transmembrane receptor belonging to the class E scavenger receptor (SR-E) subfamily of the C-type lectin family. It binds and supports the internalization of multiple structurally unrelated macromolecules. It exists on the cell surface as covalent homodimers, which can further associate into non-covalently-linked oligomers. Cell surface LOX-1 can also be cleaved to release the soluble LOX-1 extracellular domain.

Synonyms

Olr1; LOX1; LOXIN; SLOX1; CLEC8A; SCARE1

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