anti-human NKG2A monoclonal antibody Anti-Human 50 µg,Reliatech,101-M583
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of NKG2A.
Host
Mouse
Reactivity
Human
Application
WB
Platform ID
BAB250070697
Reliatech
Contact
Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989
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Product Specifications
Scientific Background
Synonyms
Specifications
Nameanti-human NKG2A monoclonal antibody Anti-Human 50 µg
Cat. No.101-M583
Accession NumberP26715
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB
Clone Number(#8S36)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only
Scientific Background
NKG2A and NKG2C are type II transmembrane proteins with extracellular C-type lectin domains. These proteins heterodimerize with CD94 to form complexes that recognize HLA-E as ligand. The NKG2A/CD94 complex delivers an inhibitory signal resulting from ITIMs within the NKG2A cytoplasmic domain. NKG2C/CD94 provides an activating signal due to association with the ITAM-containing DAP12 adapter protein. These complexes are expressed on NK and T cell subsets.
Synonyms
KLRC1; NKG2; NKG2A; CD159A
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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