anti-human Presenilin-1 monoclonal antibody Anti-Human 100 µg,Reliatech,101-M608
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with recombinant human Presenilin-1.
Host
Mouse
Reactivity
Human
Application
WB, IHC (P)
Platform ID
BAB687939270
Reliatech
Contact
Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989
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Product Specifications
Scientific Background
Synonyms
Specifications
Nameanti-human Presenilin-1 monoclonal antibody Anti-Human 100 µg
Cat. No.101-M608
Accession NumberP49768
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB, IHC (P)
Clone Number(#7G6)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only
Scientific Background
Presenilin1 (PS1) is a 467 amino acid multipass lysosomal membrane protein that is a component of the gamma secretase complex. It is cleaved by endoproteolysis at or near amino acid 298 to generate N- and C- terminal fragments. Some mutations in PS 1 are associated with the risk of early onset familial Alzheimer's disease.
Synonyms
PSEN1; AD3; FAD; PS1; PS-1; S182
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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