anti-human TMEFF1 monoclonal antibody Anti-Human 100 µg,Reliatech,101-M650

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of Human Transmembrane protein wth EGF-like and two Follistatin-like domains (TMEFF1), also called Tomoregulin-1.

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB438613946

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human TMEFF1 monoclonal antibody Anti-Human 100 µg
Cat. No.101-M650
Accession NumberQ8IYR6
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB
Clone Number(#7S12)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Transmembrane Protein with EGF-like and two Follistatin-like domains 1 (TMEFF1) also known as tomoregulin-1 is a type I transmembrane glycoprotein. TMEFF1 contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain of TMEFF1 can be released as a soluble protein. TMEFF1 is predominantly expressed in brain, but is downregulated in brain neoplasms. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.

Synonyms

TMEFF1; TR-1; H7365; C9orf2; CT120.1

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