anti-human TNFSF4 monoclonal antibody Anti-Human 100 µg,Reliatech,101-M681

This antibody war produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human TNFSF4, also called Ox40 ligand. The IgG fraction of culture supernatant was purified by Protein G affinity chromatography.

Host

Mouse

Reactivity

Human

Application

IHC (F), FC, N

Platform ID

BAB126407555

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human TNFSF4 monoclonal antibody Anti-Human 100 µg
Cat. No.101-M681
Accession NumberP23510
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC (F), FC, N
Working DilutionsFC: 1:50-100; IHC (frozen): 1:20-200; Neutralization: In the presence of 10 ng/ml recombinant human OX40, ED50 of mouse anti-human Ox40L (101-M681; #8S23) is 0.5-1.5 µg/ml. --> The dose of the neutralization assay is for reference only and the final dose
Clone Number(#8S23)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

OX40 Ligand (OX40L), also known as gp34, is a member of the TNF superfamily. Human OX40L shares 46% amino acid sequence identity with its mouse counterpart. OX40L is expressed on the surface of activated B cells, T cells, dendritic cells and endothelial cells. Similar to other TNF superfamily members, membrane-bound OX40 Ligand exists as a homotrimer. OX40L binds to OX40 (CD134), a member of the TNF receptor superfamily, which is expressed predominantly on activated CD4+ T cells.

Synonyms

TNFSF4; GP34; CD252; OX4OL; TXGP1; CD134L; OX-40L; Ox 40 Ligand

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