anti-human TROP-2 monoclonal antibody Anti-Human 50 µg,Reliatech,101-M691

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human TROP-2 recombinant protein.

Host

Mouse

Reactivity

Human

Application

WB, FC

Platform ID

BAB626557483

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human TROP-2 monoclonal antibody Anti-Human 50 µg
Cat. No.101-M691
Accession NumberP09758
HostMouse
IsotypeIgG2A
ReactivityHuman
ApplicationWB, FC
Clone Number(#49D6)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Human TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It is related to EpCAM, also called TROP-1, gp40 and KSA. A study of these two genes suggests that TROP-2 was generated through the retropositioning of the EpCAM gene. TROP-2 and EpCAM share approximately 49% amino acid sequence identity and approximately 67% similarity. Mature human and mouse TROP-2 share 80% amino acid identity.

Synonyms

TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1

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