anti-human Transferrin R monoclonal antibody Anti-Human 50 µg,Reliatech,101-M765

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TfR extracellular domain.

Host

Mouse

Reactivity

Human

Application

FC

Platform ID

BAB188988766

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-human Transferrin R monoclonal antibody Anti-Human 50 µg
Cat. No.101-M765
Accession NumberP02786
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFC
Working DilutionsThis antibody was selected for its ability to detect human Transferrin R (CD71) in direct ELISAs.
Clone Number(#7W11)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Transferrin receptors are transmembrane, homodimeric proteins that play a role in iron transport, uptake, and storage. TfR is an essential receptor, found on almost all cell types, regulated by intracellular iron concentration, and has a high affiinity for transferrin. Soluble TfR (sTfR) arises from the proteolysis of TfR into monomers that can be measured in plasma and serum. TfR2 has limited tissue distribution (hepatocytes and enterocytes), is regulated by the cell cycle, and binds transferrin poorly.

Synonyms

TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR

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