anti-human UNC5H3 monoclonal antibody Anti-Human 100 µg,Reliatech,101-M696
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of Human UNC5H3 recombinant protein.
Host
Mouse
Reactivity
Human
Application
WB, IHC (P)
Platform ID
BAB814101212

Reliatech
Contact
Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989
Email:
Specifications
Scientific Background
Members of the UNC5H family are best known as receptors for the axon guidance molecule netrin. Structurally, UNC5Hs have two Ig and two thrombospondin type 1 domains in their extracellular region, and a conserved ZU-5 domain, a deleted in colorectal cancer (DCC)-binding domain, and a C-terminal death domain in their cytoplasmic region. In general, they mediate the chemorepulsive effects of netrin, while the other netrin receptor subtype, DCC, mediates attraction. Members of the UNC5H family have also been implicated as tumor suppressors and regulators of apoptosis.
Synonyms
UNC5C; UNC5H3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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