anti-mouse CD3e monoclonal antibody Anti-Mouse 50 µg,Reliatech,103-M516

Host

Hamster

Application

FC, IP

Platform ID

BAB246472425

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-mouse CD3e monoclonal antibody Anti-Mouse 50 µg
Cat. No.103-M516
Accession NumberP22646
HostHamster
IsotypeIgG
ApplicationFC, IP
Clone Number(#1T29)
Regulatory StatusFor research use only

Scientific Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women

Synonyms

T-cell surface antigen T3/Leu-4 epsilon chain

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