anti-mouse Cerberus-1 monoclonal antibody Anti-Mouse 100 µg,Reliatech,103-M345

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of Cerberus 1.

Host

Rat

Reactivity

Mouse

Application

WB

Platform ID

BAB621659835

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-mouse Cerberus-1 monoclonal antibody Anti-Mouse 100 µg
Cat. No.103-M345
Accession NumberO55233
HostRat
IsotypeIgG2
ReactivityMouse
ApplicationWB
Clone Number(#8K12)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Cerberus 1, also called DAND4, is a member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus; DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. Cerberus-S, which is generated by proteolysis in Xenopus, is a short version of the molecule and includes the C-terminal cysteine knot domain.

Synonyms

Cer1; Cerl; Cerl1; Cerr1; cer-1

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