anti-mouse Emilin-1 monoclonal antibody Anti-Mouse 100 µg,Reliatech,103-M80

Host

Rat

Reactivity

Mouse

Application

WB, IHC (F)

Platform ID

BAB372434463

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-mouse Emilin-1 monoclonal antibody Anti-Mouse 100 µg
Cat. No.103-M80
Accession NumberQ99K41
HostRat
ReactivityMouse
ApplicationWB, IHC (F)
Working DilutionsWestern Blot: use at 2-10 µg/ml.
Clone Number(#C11A8)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
StorageThe lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50%
Regulatory StatusFor research use only

Scientific Background

Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.

Synonyms

gp115; AW229038; BB105748; EMILIN-1; 5830419M17Rik; elastin microfibril interface located protein 1

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