anti-mouse IGF-BP5 monoclonal antibody Anti-Mouse 100 µg,Reliatech,103-M238
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant protein of IGFBP-5.
Host
Rat
Reactivity
Mouse
Application
WB
Platform ID
BAB185990206
Reliatech
Contact
Tel: +49 (0) 5331 - 8586987
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Product Specifications
Scientific Background
Synonyms
Specifications
Nameanti-mouse IGF-BP5 monoclonal antibody Anti-Mouse 100 µg
Cat. No.103-M238
Accession NumberQ07079
HostRat
IsotypeIgG2
ReactivityMouse
ApplicationWB
Clone Number(#12C23)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only
Scientific Background
IGFBP5 is expressed by fibroblasts, myoblasts and osteoblasts, making it the predominant IGFBP found in bone extracts. IGFBP5 has a strong affinity for hydroxyapatite, allowing it to bind to bone cells. When bound to extracelluar matrix, IGFBP5 is protected from proteolysis and potentiates IGF activity, but when it is soluble, IGFBP5 is cleaved to a biologically inactive 21 kDa fragment. Mouse, human and rat IGFBP5 share 97% identity.
Synonyms
Igfbp5; IGFBP-5; AI256729; AW208790; IGFBP-5P
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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