anti-mouse IL-1 R1 monoclonal antibody Anti-Mouse 100 µg,Reliatech,103-M136

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant extracellular domain of mouse IL-1 R1 protein. IgG2 fraction of the tissue culture supernatant was purified by Protein G affini

Host

Rat

Reactivity

Mouse

Application

WB

Platform ID

BAB498596405

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-mouse IL-1 R1 monoclonal antibody Anti-Mouse 100 µg
Cat. No.103-M136
Accession NumberP13504
HostRat
IsotypeIgG2
ReactivityMouse
ApplicationWB
Clone Number(#11B7)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

IL-1 receptor type I (IL1R-I) is an 80 kD transmembrane glycoprotein and a member of the immunoglobulin superfamily expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. IL1R-I binds the mature forms of IL-1α, IL-1β, and IL-1Ra proteins. High affinity binding and signaling by the type I IL-1 receptor requires CD121a and the accessory protein, IL-1R AcP, which does not bind IL-1 alone, but forms a dimer capable of binding IL-1.

Synonyms

Il1r1; IL-iR; CD121a; CD121b; Il1r-1; Interleukin 1 receptor 1

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