anti-mouse IL-1 R1 monoclonal antibody Anti-Mouse 100 µg,Reliatech,103-M136
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant extracellular domain of mouse IL-1 R1 protein. IgG2 fraction of the tissue culture supernatant was purified by Protein G affini
Host
Rat
Reactivity
Mouse
Application
WB
Platform ID
BAB498596405

Reliatech
Contact
Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989
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Specifications
Scientific Background
IL-1 receptor type I (IL1R-I) is an 80 kD transmembrane glycoprotein and a member of the immunoglobulin superfamily expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. IL1R-I binds the mature forms of IL-1α, IL-1β, and IL-1Ra proteins. High affinity binding and signaling by the type I IL-1 receptor requires CD121a and the accessory protein, IL-1R AcP, which does not bind IL-1 alone, but forms a dimer capable of binding IL-1.
Synonyms
Il1r1; IL-iR; CD121a; CD121b; Il1r-1; Interleukin 1 receptor 1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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