anti-mouse IL-4 receptor alpha monoclonal antibody Anti-Mouse 100 µg,Reliatech,103-M254

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-4R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinit

Host

Rat

Reactivity

Mouse

Application

WB

Platform ID

BAB686639894

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Nameanti-mouse IL-4 receptor alpha monoclonal antibody Anti-Mouse 100 µg
Cat. No.103-M254
Accession NumberP16382
HostRat
IsotypeIgG2
ReactivityMouse
ApplicationWB
Clone Number(#16F23)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Two types of IL-4 receptor complexes have been described. The typeI IL-4 receptor complex is composed of a high-affinity IL-4-binding subunit (referred to as IL-4 R or IL-4 R alpha) and the common gamma chain that does not bind IL-4 by itself. The type II IL-4 receptor complex is composed of IL-4 R and IL-13 R alpha 1. Besides IL-4 signals, the type II IL-4 receptor complex can also transduce IL-13 signals. In the type II complex, IL-4 R subunit binds only IL-4 and not IL-13. Similarly, the IL-13 R alpha 1 subunit binds only IL-13 and not IL-4.

Synonyms

Il4ra; Il4r; CD124

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.