anti-mouse Marapsin monoclonal antibody Anti-Mouse 100 µg,Reliatech,103-M433

Marapsin, Pancreasin, and channel-activating protease 2 (CAP2), encoded by the Prss27 gene, are different names given for the same serine protease that is expressed strongly in the pancreas. The mouse protein is synthesized with a signal peptide (amino acid residues 1-22), a pro peptide (residues 23-37)and amature chain (residues 38-290)corresponding to the serine protease domain. The fulllengthprotein was expressed and the secreted protein purified. The N-terminalsequencing results indicate that the purified protein is a disulfide bond-linked dimer formed between the pro peptide and the mature chain. The active enzyme has lowactivity against peptide substrates tested, but high activity against thioester substrates. The peptidase activity is inhibited by 20 mM benzamidine.

Prss27; Mpn; CAPH2; marapsin