beta III Tubulin Antibody (YA4243),MedChemexpress,HY-P84546
beta III Tubulin Antibody (YA4243) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TUBB3. It can be used as a loading control antibody.
Host
Mouse
Reactivity
Human,Mouse,Rat
Application
WB,ICC/IF,FC,ELISA
Conjugate
Non-conjugated
Platform ID
BAB401868145
Suppliers
(1)Biomedical Life sciences
MedChemexpress
Master of Bioactive Molecules
Contact
Tel: 609-228-6898
Fax: 609-228-5909
Email:
Specifications
Verification Image
Scientific Background
TUBB3 is a key member of the tubulin family, forming microtubules primarily composed of alpha- and beta-tubulin heterodimers. Microtubules grow by adding GTP-tubulin dimers at their ends, forming a stabilizing cap. Below this cap, alpha-beta tubulin heterodimers remain in a GDP-bound state due to alpha-tubulin's GTPase activity. TUBB3 plays a critical role in axon guidance and maintenance. The binding of NTN1/Netrin-1 to its receptor UNC5C may dissociate UNC5C from polymerized microtubules, increasing microtubule dynamics and mediating axon repulsion. It also contributes to dorsal root ganglion axon projection toward the spinal cord.
Synonyms
tubulin, beta 3; MC1R; TUBB4
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Loading Controls
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