eIF2 alpha antibody [3H4],Genetex,GTX84579

Host

Mouse

Reactivity

Human, Rat, Dog, Monkey

Application

WB ICC/IF IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB446453859

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameeIF2 alpha antibody [3H4]
Cat. No.GTX84579
Gene ID (Entrez)1965
HostMouse
IsotypeIgG1
ReactivityHuman, Rat, Dog, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P FCM
ClonalityMonoclonal
Concentration0.69 mg/ml (Please refer to the vial label for the specific concentration.)
TargetEIF2S1
ImmunogenFull length human recombinant protein of human EIF2S1 (NP_004085) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Synonyms

eukaryotic translation initiation factor 2 subunit alpha , EIF-2 , EIF-2A , EIF-2alpha , EIF2 , EIF2A

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