eIF4E (phospho Ser209) antibody,Genetex,GTX24774

Host

Rabbit

Reactivity

Human, Mouse, Rat, Rabbit

Application

WB ICC/IF FCM

Conjugate

Unconjugated

Platform ID

BAB615628938

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameeIF4E (phospho Ser209) antibody
Cat. No.GTX24774
Gene ID (Entrez)1977
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Rabbit
ConjugationUnconjugated
ApplicationWB ICC/IF FCM
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetEIF4E
ImmunogenThe antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human eIF4E that contains serine 209. The sequence is conserved in mouse, rat and rabbit.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS, 0.1% BSA, 50% Glycerol,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Synonyms

eukaryotic translation initiation factor 4E , AUTS19 , CBP , EIF4E1 , EIF4EL1 , EIF4F , eIF-4E

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