gamma Sarcoglycan antibody,Genetex,GTX117176

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB IHC-P IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB827072454

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Namegamma Sarcoglycan antibody
Cat. No.GTX117176
Gene ID (Entrez)6445
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P IHC-Fr
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSGCG
ImmunogenRecombinant protein encompassing a sequence within the Extracellular domain of human Gamma Sarcoglycan. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]

Synonyms

sarcoglycan gamma , 35DAG , A4 , DAGA4 , DMDA , DMDA1 , LGMD2C , LGMDR5 , MAM , SCARMD2 , SCG3 , gamma-SG

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