mAChR M2 antibody [B8E5],Genetex,GTX54482

Host

Mouse

Reactivity

Human, Mouse, Rat, Guinea pig

Application

WB ICC/IF IHC-Fr ELISA Functional Assay

Conjugate

Unconjugated

Platform ID

BAB442467038

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NamemAChR M2 antibody [B8E5]
Cat. No.GTX54482
Gene ID (Entrez)1129
HostMouse
IsotypeIgG2a
ReactivityHuman, Mouse, Rat, Guinea pig
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-Fr ELISA Functional Assay
ClonalityMonoclonal
Concentration100 μg/ml (Please refer to the vial label for the specific concentration.)
TargetCHRM2
ImmunogenPeptide VRTVEDGECYIQFFSNAAVTFGTAI(C): Human second extracellular loop residues 168-192
PurityPurified IgG2a
Appearance/FormLiquid
FormulationFilter-sterilized PBS, 0.1% BSA,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Synonyms

CHRM2,HM2,cholinergic receptor muscarinic 2,mAChR M2,Muscarinic Acetylcholine Receptor 2

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