n-Myc antibody [NMYC-1],Genetex,GTX20057

Host

Mouse

Reactivity

Human, Mouse

Application

WB ICC/IF FCM IP ChIP assay Gel supershift assays MS

Conjugate

Unconjugated

Platform ID

BAB047800247

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

Namen-Myc antibody [NMYC-1]
Cat. No.GTX20057
Gene ID (Entrez)4613
HostMouse
IsotypeIgG2a
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF FCM IP ChIP assay Gel supershift assays MS
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetMYCN
ImmunogenA synthetic peptide (SPYVESEDAPPQKC) conjugated to KLH, corresponding to amino acids 327-339 of human n-Myc. [UniProt# P04198]
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq]

Synonyms

MYCN proto-oncogene, bHLH transcription factor , MODED , N-myc , NMYC , ODED , bHLHe37

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